Apert syndrome is a rare genetic condition that can cause the skull to grow abnormally. Apert syndrome is a disorder that is marked by abnormal growth of skull bones. Almost all cases of Apert syndrome result from new mutations in the gene, and occur in people with no history of the disorder in their family. Apert syndrome is primarily characterized by a fusion of the skull bones that occurs too early during development (craniosynostosis) and webbing of the fingers and toes (syndactyly). The early fusion of the skull causes the head to be cone-shaped (acrocephaly). Apert syndrome derives its name from that of the French physician, Eugene Apert, who produced detailed case studies of this condition. Apert syndrome is a form of acrocephalosyndactyly, a congenital disorder characterized by malformations of the skull, face, hands and feet. Apert syndrome causes facial and cranial anomalies, which can cause vision and dental problems. Babies with Apert syndrome have an atypical head and face. Causes of Apert Syndrome. Individuals with Apert syndrome typically have the following conditions: More commonly though, it is a completely random occurrence. The precise cause of Apert syndrome is unknown. Apert syndrome is a rare genetic condition that is apparent at birth. Apert syndrome is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. Apert syndrome causes. As discussed above, the condition of Apert syndrome causes the poor development of the physical character that leads to several problems. It is classified as a branchial arch syndrome, affecting the first branchial (or pharyngeal) arch, the precursor of the maxilla and mandible.Disturbances in the development of the branchial arches in fetal development create lasting and widespread effects. Your head can be: Pointed at the top, a cone-shaped skull, known as turribraquicephalia. In addition to the abnormal skull such children would also have various other problems inherited by birth. Apert syndrome can also cause abnormalities in the fingers and toes. This condition is … Apert syndrome is characterized by craniosynostosis, a condition in which the fibrous joints (sutures) between bones of … Babies born with Apert syndrome may also have fingers or toes fused together. While in utero, a baby's skull can fuse prematurely, causing the face and head to change shape. What Is Apert Syndrome? This can also lead to a sunken appearance in the middle of the face (midface hypoplasia), wide-set eyes (hypertelorism), and a … There are no known causes or risk factors for Apert Syndrome. Problems caused by Apert syndrome. It can be an inherited condition—a person with the condition has a 50% chance of passing this down to his or her children. Gene mutations are responsible for causing the early fusion of the skull, hand and feet bones. Apert syndrome is a rare genetic disorder that involves premature fusing of the skull bones during the development of the fetus. Doctors believe it's probably the result of genetic mutation that occurs early on in pregnancy in a gene called "fibroblast growth factor receptor 2," or FGFR2.. Because this gene plays an important role in bone growth, disruption of it may cause the physical traits of Apert syndrome, such as: However, the syndrome also causes following problems in children suffering from the condition. People with Apert syndrome can have distinctive malformations of the skull, face, hands, and feet. Apert syndrome […] Apert syndrome, also called acrocephalosyndactyly, is a genetic syndrome characterized by anomalies of the skull, face and limbs. It is this gene that is responsible for producing and guiding a protein namely the fibroblast growth factor receptor 2 to give signals to the immature cells to take the place of the bone cells. 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